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Data sheet of Mouse Monoclonal to NR2F6
| Brand | Exbio |
| Product type | Primary antibodies |
| Reactivity | Human |
| Clonality | Monoclonal |
More info about Mouse Monoclonal to NR2F6
| Brand: | Exbio |
| Product no.: | 11-719-C025 |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Product name: | Mouse Monoclonal to NR2F6 |
| Antigen: | NR2F6 |
| Clonality: | Monoclonal |
| Clone: | EM-51 |
| Isotype: | IgG2a |
| Immunogen: | Recombinant human NR2F6 protein expressed in E. coli |
| Format: | purified |
| Specificity: | The mouse monoclonal antibody EM-51 recognizes NR2F6, a transcriptional repressor expressed mainly in the heart, placenta, liver, skeletal muscle, kidney and pancreas, but also e.g. in T cell subpopulations. |
| Categories: | Transcription Regulation & Nuclear Proteins (Human) |
| Concentration: | 1 mg/ml |
| Storage buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Storage / stability: | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
| Background: | NR2F6 (Nuclear receptor subfamily 2 group F member 6), also known as EAR2 or ERBAL2, is a transcription factor involved in modulation of hormonal responses. NR2F6 represses e.g. transcription of the oxytocin-neurophysin gene, renin gene, lutropin-choriogonadotropic hormone receptor gene, and the thyroid hormone receptor gene. In the immune system, NR2F6 affects IL-17 expression in the Th-17 cells, thus also the balance between immunological tolerance and autoimmunity. |
| Purity: | > 95% (by SDS-PAGE) |
| Purification: | Purified by protein-A affinity chromatography |
| Related products: | - Mouse Monoclonal to p21Waf1 - Mouse Monoclonal to NTAL / LAB - Mouse Monoclonal to OPAL1 |
| Shipping condition: | Room temperature |