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Data sheet of Mouse Monoclonal to IgM
| Brand | Exbio |
| Product type | Primary antibodies |
| Reactivity | Human |
| Clonality | Monoclonal |
More info about Mouse Monoclonal to IgM
| Brand: | Exbio |
| Product no.: | 11-321-C025 |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Product name: | Mouse Monoclonal to IgM |
| Antigen: | IgM |
| Clonality: | Monoclonal |
| Clone: | MA2 |
| Isotype: | IgG2b |
| Immunogen: | IgM from human serum._x000D_ |
| Format: | purified |
| Specificity: | The antibody MA2 reacts with µ-chain of human IgM, Fab - region localized epitope. |
| Categories: | Immunoglobulins (Human) |
| Concentration: | 1 mg/ml |
| Storage buffer: | Tris buffered saline (TBS) with 15 mM sodium azide, approx. pH 8.0 |
| Storage / stability: | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
| Background: | Immunoglobulin M (IgM) is produced as a 900 kDa pentamer, which is an efficient complement binder. This antibody type is produced initially in the immune response and it is the first immunoglobulin class to be synthesized by a fetus or newborn. IgM antibodies do not cross the placenta. IgM concentration in blood is 0.12 g/l and its biological survival (plasma T1/2) is 5 days. |
| Purity: | > 95% (by SDS-PAGE) |
| Purification: | Purified by precipitation and chromatography |
| General references: | *Brinkmann V, Heusser CH.: T cell-dependent differentiation of human B cells into IgM, IgG, IgA, or IgE_x000D_ plasma cells: high rate of antibody production by IgE plasma cells, but limited clonal expansion of IgE precursors. Cell Immunol. 1993 Dec;152(2):323-32._x000D_ _x000D_ _x000D_ , *Balogh Z, Merétey K, Falus A, Bozsóky S.: Serological abnormalities in juvenile chronic arthritis: a review of 46 cases. Ann Rheum Dis. 1980 Apr;39(2):129-34._x000D_ , *Fuller JM, Keyser J.W.: Serum immunoglobulins after surgical operation. Clin Chem. 1975 May;21(6):667-71._x000D_ _x000D_ , *Franklin E.C.: Structure and function of immunoglobulins. Acta Endocrinol Suppl (Copenh). 1975;194:77-95._x000D_ _x000D_ |
| Related products: | - Mouse Monoclonal to Intra-Acrosomal Protein (Canine) - Mouse Monoclonal to Ikaros - Mouse Monoclonal to Insulin |
| Shipping condition: | Room temperature |