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Data sheet of Mouse Monoclonal to Insulin
| Brand | Exbio |
| Product type | Primary antibodies |
| Reactivity | Human, Bovine, Porcine |
| Clonality | Monoclonal |
More info about Mouse Monoclonal to Insulin
| Brand: | Exbio |
| Product no.: | 11-246-C025 |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Product name: | Mouse Monoclonal to Insulin |
| Antigen: | Insulin |
| Clonality: | Monoclonal |
| Clone: | IN-05 |
| Isotype: | IgG1 |
| Immunogen: | Porcine insulin. |
| Format: | purified |
| Specificity: | The antibody IN-05 reacts with insulin, one of the major regulatory endocrine hormones of intermediate metabolism, normally secreted by the beta cells (a type of islet cells) of the pancreas; it is also present in tumors of B cell origin such as insulinoma._x000D_ _x000D_ _x000D_ _x000D_ |
| Categories: | Hormones (Veterinary), Hormones (Human) |
| Concentration: | 1 mg/ml |
| Storage buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Storage / stability: | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
| Background: | Insulin and glucagon are pancreatic endocrine hormones secreted by islet cells within the pancreas. The stimulus for insulin secretion is a HIGH blood glucose. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. |
| Purity: | > 95% (by SDS-PAGE) |
| Purification: | Purified by protein-A affinity chromatography |
| Product specific references: | *Horejsi V, Hilgert I, Kristofova H, Satayalai O: Murine hybridoma monoclonal antibodies against insulin: cross-reactivity with insulins of three species and blocking of insulin binding to its receptor. Immunol Lett. 1984;8(5):279-83. _x000D_ |
| Related products: | - Mouse Monoclonal to Ki-67 - Mouse Monoclonal to Intra-Acrosomal Protein (Canine) - Mouse Monoclonal to Kappa light chains |
| Shipping condition: | Room temperature |