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Data sheet of Mouse Monoclonal to AGR3
| Brand | Exbio |
| Product type | Primary antibodies |
| Reactivity | Human, Other species Not tested |
| Clonality | Monoclonal |
More info about Mouse Monoclonal to AGR3
| Brand: | Exbio |
| Product no.: | 11-561-C025 |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Product name: | Mouse Monoclonal to AGR3 |
| Antigen: | AGR3 |
| Clonality: | Monoclonal |
| Clone: | AGR3.2 |
| Isotype: | IgG1 |
| Immunogen: | Purified human AGR3 protein |
| Format: | purified |
| Specificity: | The antibody AGR3.2 recognizes epitope QYSQALKKV within AGR3 (AG3) protein (19-20 kDa); secreted cytoplasmic protein which can serve as a marker of carcinogenesis._x000D_ |
| Categories: | Serum & Plasma Proteins (Human) |
| Concentration: | 1 mg/ml |
| Storage buffer: | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide. |
| Storage / stability: | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
| Background: | AGR3 (Anterior Gradient 3) protein, also known as AG3 (hAG-3, HAG3 in human), or BCMP11, is a secreted cytoplasmic protein which is involved in metastasis induction and p53 tumour supressor inhibition. It may serve as molecular marker and potential therapeutic target for hormone-responsive breast tumours. Its Xenopus homolog is associated with anteroposterior fate determination during early development._x000D_ |
| Purity: | > 95% (by SDS-PAGE) |
| Purification: | Purified by protein-A affinity chromatography |
| General references: | *Fletcher GC, Patel S, Tyson K, Adam PJ, Schenker M, Loader JA, Daviet L, Legrain P, Parekh R, Harris AL, Terrett JA: hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with_x000D_ metastasis gene C4.4a and dystroglycan. Br J Cancer. 2003 Feb 24;88(4):579-85._x000D_ , *Persson S, Rosenquist M, Knoblach B, Khosravi-Far R, Sommarin M, Michalak M: Diversity of the protein disulfide isomerase family: identification of breast tumor induced Hag2 and Hag3 as novel members of the protein family. Mol Phylogenet Evol. 2005 Sep;36(3):734-40._x000D_ |
| Related products: | - Mouse Monoclonal to alpha, beta-tubulin dimer - Mouse Monoclonal to AHNAK1 - Mouse Monoclonal to Albumin |
| Shipping condition: | Room temperature |