| Brand: | Abnova |
| Reference: | H00023049-M02 |
| Product name: | SMG1 monoclonal antibody (M02), clone 1A8 |
| Product description: | Mouse monoclonal antibody raised against a partial recombinant SMG1. |
| Clone: | 1A8 |
| Isotype: | IgG2a Kappa |
| Gene id: | 23049 |
| Gene name: | SMG1 |
| Gene alias: | 61E3.4|ATX|KIAA0421|LIP |
| Gene description: | SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans) |
| Genbank accession: | NM_014006 |
| Immunogen: | SMG1 (NP_055535, 2922 a.a. ~ 3031 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Immunogen sequence/protein sequence: | PDVMSQNARKLIQKNLATSADTPPSTVPGTGKSVACSPKKAVRDPKTGKAVQERNSYAVSVWKRVKAKLEGRDVDPNRRMSVAEQVDYVIKEATNLDNLAQLYEGWTAWV |
| Protein accession: | NP_055535 |
| Storage buffer: | In 1x PBS, pH 7.4 |
| Storage instruction: | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Quality control testing: | Antibody Reactive Against Recombinant Protein. |
| Quality control testing picture: |  |
| Quality control testing picture note: | Western Blot detection against Immunogen (37.84 KDa) . |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Antigen species / target species: | Human |
| Reactivity: | Human |
| Application image: |  |
| Application image note: | Immunoperoxidase of monoclonal antibody to SMG1 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml] |
| Applications: | WB-Ce,IHC-P,S-ELISA,ELISA,WB-Re |
| Shipping condition: | Dry Ice |
| Publications: | The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8.Arias-Palomo E, Yamashita A, Fernandez IS, Nunez-Ramirez R, Bamba Y, Izumi N, Ohno S, Llorca O. Genes Dev. 2011 Jan 15;25(2):153-64. |