Brand: | Abnova |
Reference: | H00007357-M03 |
Product name: | UGCG monoclonal antibody (M03), clone 1E5 |
Product description: | Mouse monoclonal antibody raised against a partial recombinant UGCG. |
Clone: | 1E5 |
Isotype: | IgG1 Kappa |
Gene id: | 7357 |
Gene name: | UGCG |
Gene alias: | GCS |
Gene description: | UDP-glucose ceramide glucosyltransferase |
Genbank accession: | NM_003358 |
Immunogen: | UGCG (NP_003349, 33 a.a. ~ 131 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Immunogen sequence/protein sequence: | TRLHLNKKATDKQPYSKLPGVSLLKPLKGVDPNLINNLETFFELDYPKYEVLLCVQDHDDPAIDVCKKLLGKYPNVDARLFIGGKKVGINPKINNLMPG |
Protein accession: | NP_003349 |
Storage buffer: | In 1x PBS, pH 7.4 |
Storage instruction: | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
Quality control testing: | Antibody Reactive Against Recombinant Protein. |
Quality control testing picture: |  |
Quality control testing picture note: | Western Blot detection against Immunogen (36.63 KDa) . |
Product type: | Primary antibodies |
Host species: | Mouse |
Antigen species / target species: | Human |
Reactivity: | Human |
Application image: |  |
Application image note: | Detection limit for recombinant GST tagged UGCG is 0.3 ng/ml as a capture antibody. |
Applications: | WB-Ce,S-ELISA,ELISA,WB-Re |
Shipping condition: | Dry Ice |
Publications: | DNA damage induces down-regulation of UDP-glucose ceramide glucosyltransferase, increases ceramide levels and triggers apoptosis in p53-deficient cancer cells.Haynes TA, Filippov V, Filippova M, Yang J, Zhang K, Duerksen-Hughes PJ. Biochim Biophys Acta. 2012 Feb 11. [Epub ahead of print] |