Brand: | Abnova |
Reference: | H00007272-M01 |
Product name: | TTK monoclonal antibody (M01), clone 3G7 |
Product description: | Mouse monoclonal antibody raised against a partial recombinant TTK. |
Clone: | 3G7 |
Isotype: | IgG2a Kappa |
Gene id: | 7272 |
Gene name: | TTK |
Gene alias: | ESK|FLJ38280|MPS1|MPS1L1|PYT |
Gene description: | TTK protein kinase |
Genbank accession: | BC000633 |
Immunogen: | TTK (AAH00633, 1 a.a. ~ 176 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Immunogen sequence/protein sequence: | MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMANNPEDWLSLLLKLEKNSVPLSDALLNKLIGRYSQAIEALPPDKYGQNESFARIQVRFAELKAIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVP |
Protein accession: | AAH00633 |
Storage buffer: | In 1x PBS, pH 7.4 |
Storage instruction: | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
Quality control testing: | Antibody Reactive Against Recombinant Protein. |
Quality control testing picture: |  |
Quality control testing picture note: | Western Blot detection against Immunogen (44.99 KDa) . |
Product type: | Primary antibodies |
Host species: | Mouse |
Antigen species / target species: | Human |
Reactivity: | Human |
Application image: |  |
Application image note: | TTK monoclonal antibody (M01), clone 3G7 Western Blot analysis of TTK expression in K-562 ( Cat # L009V1 ). |
Applications: | WB-Ce,S-ELISA,ELISA,WB-Re,WB-Tr |
Shipping condition: | Dry Ice |
Publications: | High frequency of TTK mutations in microsatellite-unstable colorectal cancer and evaluation of their effect on spindle-assembly checkpoint.Niittymaki I, Gylfe A, Laine L, Laakso M, Lehtonen HJ, Kondelin J, Tolvanen J, Nousiainen K, Pouwels J, Jarvinen H, Nuorva K, Mecklin JP, Makinen M, Ristimaki A, Orntoft TF, Hautaniemi S, Karhu A, Kallio MJ, Aaltonen LA. Carcinogenesis. 2010 Dec 16. [Epub ahead of print] |