| Brand | Abnova | 
| Product type | Primary antibodies | 
| Reactivity | Human | 
| Host species | Rabbit | 
| Applications | IHC-P | 
| Brand: | Abnova | 
| Reference: | PAB31435 | 
| Product name: | NLRP3 polyclonal antibody | 
| Product description: | Rabbit polyclonal antibody raised against partial recombinant human NLRP3. | 
| Isotype: | IgG | 
| Gene id: | 114548 | 
| Gene name: | NLRP3 | 
| Gene alias: | AGTAVPRL|AII|AII/AVP|AVP|C1orf7|CIAS1|CLR1.1|FCAS|FCU|FLJ95925|MWS|NALP3|PYPAF1 | 
| Gene description: | NLR family, pyrin domain containing 3 | 
| Immunogen: | Recombinant protein corresponding to human NLRP3. | 
| Immunogen sequence/protein sequence: | FKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMIDFNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGLLEYLSRISICKMKKDYRKKYR | 
| Protein accession: | Q96P20 | 
| Form: | Liquid | 
| Recommend dilutions: | Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500) The optimal working dilution should be determined by the end user.  | 
| Storage buffer: | In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide). | 
| Storage instruction: | Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.  | 
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. | 
| Product type: | Primary antibodies | 
| Host species: | Rabbit | 
| Antigen species / target species: | Human | 
| Reactivity: | Human | 
| Application image: | ![]()  | 
| Application image note: | Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil with NLRP3 polyclonal antibody (Cat # PAB31435) shows moderate cytoplasmic positivity in germinal and non-germinal center cells. | 
| Applications: | IHC-P | 
| Shipping condition: | Dry Ice | 
| Publications: | Inflammasome-dependent caspase-1 activation in cervical epithelial cells stimulates growth of the intracellular pathogen Chlamydia trachomatis.Abdul-Sater AA, Koo E, Hacker G, Ojcius DM. J Biol Chem. 2009 Sep 25;284(39):26789-96. doi: 10.1074/jbc.M109.026823. Epub 2009 Jul 31.  |