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Data sheet of Mouse Monoclonal antibody to human GCN5
| Brand | ProteoGenix |
| Product type | Primary antibodies |
| Reactivity | Human, Mouse |
| Clonality | Monoclonal |
| Host species | Mouse |
| Applications | E, WB, IC |
More info about Mouse Monoclonal antibody to human GCN5
| Brand: | ProteoGenix |
| Proteogenix reference: | PTGX-GCN5-2C11 |
| Product type: | Primary antibodies |
| Clonality: | Monoclonal |
| Product name: | Mouse Monoclonal antibody to human GCN5 |
| Host species: | Mouse |
| Target species: | Human |
| Reactivity: | Human, Mouse |
| Applications: | E, WB, IC |
| Size: | 100µl |
| Clone name: | 2GCâ€2C11 |
| Uniprot: | #N/A |
| Immunogen: | synthetic peptide coupled to ovalbumin: aa 118-132 (CKCNGWKNPKPPTAP) of human GCN5-Long, identical to mouse GCN5-Long in this region. Not present in human GCN5-Short . |
| Specificity: | human and mouse GCN5-L |
| Dilution: | 1/500-1/5000 |
| Alternative names: | Anti-KAT2A / GCN5 antibody, 1110051E14Rik antibody, AW212720 antibody, EC 2.3.1.48 antibody, GCN 5 antibody, GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2 antibody, Gcn5 antibody, GCN5 general control of amino-acid synthesis 5-like 2 (yeast) antibody, GCN5L2 antibody, general control of amino acid synthesis 5-like 2 antibody, General control of amino acid synthesis protein 5-like 2 antibody, General control of amino acid synthesis, yeast, homolog-like 2 antibody, HGCN5 antibody, Histone acetyltransferase GCN5 antibody, Histone acetyltransferase KAT2A antibody, hsGCN5 antibody, K(lysine) acetyltransferase 2A antibody, KAT2 A antibody, KAT2A antibody, KAT2A_HUMAN antibody, Lysine acetyltransferase 2A antibody, MGC102791 antibody, PCAF-b antibody, STAF97 antibody |
| Isotype: | IgG1, k |
| Form: | liquid/frozen |
| Spec:conjugate/tag/label: | Unconjugated |
| Research area: | Epigenetics & Nuclear Signalling |
| Background information: | Mouse monoclonal anti-GCN5 antibody, clone 2GC-2C11 recognize human and mouse GCN5-L. GCN5 (General control of nutrition 5, KAT2A) is a histone acetyltransferase (HAT) and has a function of transcription activator. Component of the SAGA and ATAC complexes, which have histone acetyltransferase activity for histones H3 and H4. In case of HIV-1 infection, it is inducted by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. GCN5 is required for neural tube closure and embryonic development. |
| Publications: | 1. Brand M, Moggs JG, Oulad-Abdelghani M, Lejeune F, Dilworth FJ, et al. (2001) UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation. Embo J 20: 3187-3196. 2. Helmlinger D, Hardy S, Abou-Sleymane G, Eberlin A, Bowman AB, Gansmüller A, Picaud S, Zoghbi HY, Trottier Y, Tora L, Devys D. Glutamine-expanded ataxin-7 alters TFTC/STAGA recruitment and chromatin structure leading to photoreceptor dysfunction. PLoS Biol. 2006 Mar;4(3):e67. Epub 2006 Feb 28. |
| Storage: | Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Delivery lead time in business days in europe: | 2-3 |
| Delivery conditions: | Dry Ice |
| Image: |  |
| Related products: | - Mouse Monoclonal antibody to GFP (Enhanced green fluorescent protein) - Mouse Monoclonal antibody to GFP (Enhanced green fluorescent protein) - Mouse Monoclonal antibody to human GSkâ€3 |