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Data sheet of Mouse Monoclonal to Thyroglobulin
| Brand | Exbio |
| Product type | Primary antibodies |
| Reactivity | Human |
| Clonality | Monoclonal |
More info about Mouse Monoclonal to Thyroglobulin
| Brand: | Exbio |
| Product no.: | 11-466-C025 |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Product name: | Mouse Monoclonal to Thyroglobulin |
| Antigen: | Thyroglobulin |
| Clonality: | Monoclonal |
| Clone: | 2H11 |
| Isotype: | IgG1 |
| Immunogen: | thyroid follicular cells |
| Format: | purified |
| Specificity: | The antibody 2H11 recognizes antigen thyroglobulin (TG), a 610 kDa extracellular secreted glycoprotein specific to the thyroid gland. TG is mainly expressed on thyroid follicular cells (99,1 %). |
| Categories: | Hormones (Human) |
| Concentration: | 1 mg/ml |
| Storage buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Storage / stability: | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
| Background: | Thyroid disorders are often associated with autoimmune diseases and thyroid cancer. |
| Purity: | > 95% (by SDS-PAGE) |
| Purification: | Purified by protein-A affinity chromatography |
| Product specific references: | *Magro G, Perissinotto D, Schiappacassi M, Goletz S, Otto A, Müller EC, Bisceglia M, Brown G, Ellis T, Grasso S, Colombatti A, Perris R: Proteomic and postproteomic characterization of keratan sulfate-glycanated isoforms of thyroglobulin and transferrin uniquely elaborated by papillary thyroid carcinomas. Am J Pathol. 2003 Jul;163(1):183-96. |
| General references: | Lazar V, Bidart JM, Caillou B, Mahe C, Lacroix L, Filetti S, Schlumberger M: Expression of the Na+/I- symporter gene in human thyroid tumors: a comparison study with other thyroid-specific genes. J Clin Endocrinol Metab. 1999 Sep;84(9):3228-34. _x000D_ , Emerson CH, Torres MS: Recombinant human thyroid-stimulating hormone: pharmacology, clinical applications and potential uses. BioDrugs. 2003;17(1):19-38. Review. _x000D_ , Hishinuma A, Takamatsu J, Ohyama Y, Yokozawa T, Kanno Y, Kuma K, Yoshida S, Matsuura N, Ieiri T: Two novel cysteine substitutions (C1263R and C1995S) of thyroglobulin cause a defect in intracellular transport of thyroglobulin in patients with congenital goiter and the variant type of adenomatous goiter. J Clin Endocrinol Metab. 1999 Apr;84(4):1438-44. |
| Related products: | - Mouse Monoclonal to Transferrin - Mouse Monoclonal to TNF-alpha - Mouse Monoclonal to TPX2 |
| Shipping condition: | Room temperature |