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Data sheet of Rabbit Polyclonal to Mycobacterium tuberculosis antigen Acr1
| Brand | Exbio |
| Product type | Primary antibodies |
| Reactivity | Mycobacterium tuberculosis |
| Clonality | Polyclonal |
More info about Rabbit Polyclonal to Mycobacterium tuberculosis antigen Acr1
| Brand: | Exbio |
| Product no.: | 11-185-C100 |
| Product type: | Primary antibodies |
| Host species: | Rabbit |
| Product name: | Rabbit Polyclonal to Mycobacterium tuberculosis antigen Acr1 |
| Antigen: | Mycobacterium tuberculosis antigen Acr1 |
| Clonality: | Polyclonal |
| Clone: | Polyclonal |
| Immunogen: | Recombinant Mycobacterium tuberculosis Acr1 produced in E. coli |
| Format: | purified |
| Specificity: | The rabbit polyclonal antibody to Acr1 reacts with Mycobacterium tuberculosis protein Acr1 (Rv2031c, Hsp16.3). |
| Categories: | Virology and Microbiology |
| Concentration: | 1 mg/ml |
| Storage buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Storage / stability: | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
| Background: | The Mycobacterium tuberculosis antigen Acr1 (alpha-crystallin-related protein 1), also known as Hsp16.3, is a small heat shock protein (16 kDa), which forms oligomeric assemblies. Expression of Acr1 is induced by exposure to hypoxia or nitric oxide and is associated with bacterial persistence in a non-replicating state. |
| Purity: | > 95% (by SDS-PAGE) |
| Purification: | Purified from rabbit serum by affinity chromatography |
| General references: | *Meintjes G, Skolimowska KH, Wilkinson KA, Matthews K, Tadokera R, Conesa-Botella A, Seldon R, Rangaka MX, Rebe K, Pepper DJ, Morroni C, Colebunders R, Maartens G, Wilkinson RJ: Corticosteroid-modulated immune activation in the tuberculosis immune reconstitution inflammatory syndrome. Am J Respir Crit Care Med. 2012 Aug 15;186(4):369-77, *Kennaway CK, Benesch JL, Gohlke U, Wang L, Robinson CV, Orlova EV, Saibil HR, Keep NH: Dodecameric structure of the small heat shock protein Acr1 from Mycobacterium tuberculosis. J Biol Chem. 2005 Sep 30;280(39):33419-25., Shi C, Zhang H, Zhang T, Wang X, Bai B, Zhao Y, Zhang C, Xu Z: New alternative vaccine component against mycobacterium tuberculosis--heat shock protein 16.3 or its T-cell epitope. Scand J Immunol. 2009 Nov;70(5):465-74. |
| Related products: | - Rabbit Polyclonal to Mycobacterium tuberculosis antigen EsaT-6 (Rv3875) - Rabbit Polyclonal to Mycobacterium tuberculosis antigen Acr2 - Rabbit Polyclonal to Mycobacterium tuberculosis antigen CFP10 (Rv3874) |
| Shipping condition: | Room temperature |