| Brand | Exbio | 
| Product type | Primary antibodies | 
| Reactivity | Human | 
| Clonality | Monoclonal | 
| Brand: | Exbio | 
| Product no.: | 11-244-C025 | 
| Product type: | Primary antibodies | 
| Host species: | Mouse | 
| Product name: | Mouse Monoclonal to Kappa light chains | 
| Antigen: | Kappa light chains | 
| Clonality: | Monoclonal | 
| Clone: | MEM-09 | 
| Isotype: | IgG1 | 
| Immunogen: | Crude thymus membrane fraction. | 
| Format: | purified | 
| Specificity: | The antibody MEM-09 reacts with both secreted and B cell-surface human immunoglobulin, specifically reacts with kappa light chains (22.5 kDa).  Material immunoprecipitated from human serum with the antibody MEM-09 consists of IgG and traces of IgM._x000D_ _x000D_  | 
| Categories: | Immunoglobulins (Human) | 
| Concentration: | 1 mg/ml | 
| Storage buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 | 
| Storage / stability: | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. | 
| Background: | Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda; both having a molecular weight of 22.5kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30. | 
| Purity: | > 95% (by SDS-PAGE) | 
| Purification: | Purified by protein-A affinity chromatography | 
| Product specific references: | *Horejsi V, Hilgert I, Kristofova H, Bazil V, Bukovsky A, Kulhankova J: Monoclonal antibodies against human leucocyte antigens. I. Antibodies against beta-2-microglobulin, immunoglobulin kappa light chains, HLA-DR-like antigens, T8 antigen, T1 antigen, a monocyte antigen, and a pan-leucocyte antigen. Folia Biol (Praha). 1986;32(1):12-25. _x000D_ | 
| General references: | *Franklin EC: Structure and function of immunoglobulins. Acta Endocrinol Suppl (Copenh). 1975;194:77-95._x000D_ | 
| Related products: | - Mouse Monoclonal to Ku80 Antigen / DNA helicase p80 - Mouse Monoclonal to Ki-67 - Mouse Monoclonal to Kinesin (heavy chain)  | 
| Shipping condition: | Room temperature |