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Data sheet of Rabbit Polyclonal to Csk
| Brand | Exbio |
| Product type | Primary antibodies |
| Reactivity | Human |
| Clonality | Polyclonal |
| Host species | Rabbit |
| Applications | WB |
More info about Rabbit Polyclonal to Csk
| Brand: | Exbio |
| Product no.: | 11-462-C025 |
| Product name: | Rabbit Polyclonal to Csk |
| Antigen: | Csk |
| Clonality: | Polyclonal |
| Clone: | Polyclonal |
| Immunogen: | Bacterially expressed recombinant protein corresponding to C-terminal part (residues 330-450) of Csk. |
| Format: | purified |
| Specificity: | The polyclonal antibody detects total level of endogenous Csk protein. |
| Categories: | Phosphorylation (Kinases, Phosphatases, Phosphotyrosine) (Human), Phosphorylation (Kinases, Phosphatases, Phosphotyrosine) |
| Concentration: | 1 mg/ml |
| Storage buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Storage / stability: | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
| Background: | C-terminal Src kinase (Csk) is a non-receptor protein tyrosine kinase. One of its major functions is to specifically phosphorylate a conserved C-terminal tyrosine of Src family kinases thereby down-regulating their kinase activity. CSK is expressed ubiquitously as a protein of approximately 50 KDa in cytosol, but a fraction distributes to lipid rafts due to interaction with the lipid raft-associated protein PAG (Csk-binding protein). |
| Purity: | > 95% (by SDS-PAGE) |
| Purification: | Purified from rabbit serum by protein-A afinity chromatography |
| Shipping condition: | Room temperature |