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Data sheet of Mouse Monoclonal to CLIC5a
| Brand | Exbio |
| Product type | Primary antibodies |
| Reactivity | Human |
| Clonality | Monoclonal |
More info about Mouse Monoclonal to CLIC5a
| Brand: | Exbio |
| Product no.: | 11-701-C025 |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Product name: | Mouse Monoclonal to CLIC5a |
| Antigen: | CLIC5a |
| Clonality: | Monoclonal |
| Clone: | CLIC5-02 |
| Isotype: | IgG2b |
| Immunogen: | KLH-conjugated peptide corresponding to the amino acids 160-173 of human CLIC5a |
| Format: | purified |
| Specificity: | Mouse monoclonal antibody CLIC5-02 recognizes CLIC5a, a 32 kDa protein which is component of actin complexes. Crossreactivity with CLIC5b was not determined. |
| Categories: | Cytoskeleton: Actin System (Human) |
| Concentration: | 1 mg/ml |
| Storage buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Storage / stability: | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
| Background: | CLIC5a belongs to the family of chloride intracellular channel (CLIC) proteins, all sharing a highly conserved C terminus and variable N terminus. Human CLIC5 is transcribed in two isoforms, 32 kDa CLIC5a (251 amino acids) and 49 kDa CLIC5b (410 amino acids). These proteins exist in a soluble form and their function as ion channels in vitro has not been fully confirmed in vivo. CLIC5a is a component of complexes of actin, ezrin, and several other actin-associated proteins and is important for functionality of actin-based structures. |
| Purity: | > 95% (by SDS-PAGE) |
| Purification: | Purified by protein-A affinity chromatography |
| General references: | *Wegner B, Al-Momany A, Kulak SC, Kozlowski K, Obeidat M, Jahroudi N, Paes J, Berryman M, Ballermann BJ: CLIC5A, a component of the ezrin-podocalyxin complex in glomeruli, is a determinant of podocyte integrity. Am J Physiol Renal Physiol. 2010 Jun;298(6):F1492-503. |
| Related products: | - Mouse Monoclonal to C-peptide - Mouse Monoclonal to Clusterin / Apolipoprotein J - Mouse Monoclonal to c-Myc / Cellular myelocytomatosis oncogene |
| Shipping condition: | Room temperature |