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Data sheet of Mouse Monoclonal to CD328 / Siglec-7
| Brand | Exbio |
| Product type | Primary antibodies |
| Reactivity | Human |
| Clonality | Monoclonal |
More info about Mouse Monoclonal to CD328 / Siglec-7
| Brand: | Exbio |
| Product no.: | 11-799-C025 |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Product name: | Mouse Monoclonal to CD328 / Siglec-7 |
| Antigen: | CD328 / Siglec-7 |
| Clonality: | Monoclonal |
| Clone: | 6-434 |
| Isotype: | IgG1 |
| Immunogen: | human dendritic cells |
| Format: | purified |
| Specificity: | The mouse monoclonal antibody 6-434 recognizes CD328 (Siglec-7), a 75 kDa transmembrane glycoprotein expressed mainly on NK cells, dendritic cells and monocytes. _x000D_ _x000D_ HLDA 8; WS Code ARN-80652 _x000D_ |
| Categories: | CD and Related Antigens (Human) |
| Concentration: | 1 mg/ml |
| Storage buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Storage / stability: | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
| Background: | CD328, also known as Siglec-7 or p75/AIRM1, is a 75 kDa type I transmembrane glycoprotein of sialic acid-binding immunoglobulin-like lectin (Siglec) family. CD328 binds to sialylated glycans with alpha2,6 sialyl and alpha2,8 disyalyl residues and mediates sialic acid-dependent cell-cell binding. As it contains in its intracellular part the immunoreceptor tyrosine-based inhibitory motif (ITIM), it serves as an inhibitory receptor, e.g. of NK cells. |
| Purity: | > 95% (by SDS-PAGE) |
| Purification: | Purified by protein-A affinity chromatography |
| Related products: | - Mouse Monoclonal to CD34 - Mouse Monoclonal to CD33 - Mouse Monoclonal to CD334 / FGFR4 |
| Shipping condition: | Room temperature |