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Data sheet of Rat Monoclonal to CD267 / TACI
| Brand | Exbio |
| Product type | Primary antibodies |
| Reactivity | Human |
| Clonality | Monoclonal |
More info about Rat Monoclonal to CD267 / TACI
| Brand: | Exbio |
| Product no.: | 11-162-C025 |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Product name: | Rat Monoclonal to CD267 / TACI |
| Antigen: | CD267 / TACI |
| Clonality: | Monoclonal |
| Clone: | 1A1 |
| Isotype: | IgG2a |
| Immunogen: | CD267-transfected RBL cells |
| Format: | purified |
| Specificity: | The rat monoclonal antibody 1A1 recognizes CD267 / TACI, a 32 kDa type III transmembrane protein expressed by B cells and possibly by some activated T cells._x000D_ _x000D_ HLDA 8 Workshop |
| Categories: | CD and Related Antigens (Human) |
| Concentration: | 1 mg/ml |
| Storage buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Storage / stability: | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
| Background: | CD267 / TACI (Transmembrane Activator Calcium modulator and cyclophilin ligand Interactor), a TNFR superfamily transmembrane protein, is expressed on B cells (predominantly on CD27+ memory cells), multiple myeloma cells and B cell chronic lymphocytic leukemia (B-CLL). Its triggering leads to activation of the transcription factors NFAT, AP1, and NF-kappa-B. It plays a crucial role in humoral immunity. Mutations in CD267 are associated with common variable immunodeficiency and IgA deficiency. |
| Purity: | > 95% (by SDS-PAGE) |
| Purification: | Purified by protein-A affinity chromatography |
| Product specific references: | *Koarada S, Tada Y, Suematsu R, Soejima S, Inoue H, Ohta A, Nagasawa K: Phenotyping of P105-negative B cell subsets in patients with systemic lupus erythematosus. Clin Dev Immunol. 2012;2012:198206. |
| Related products: | - Rat Monoclonal to CD44 - Rat Monoclonal to CD4 (mouse) - Rat Monoclonal to CD41 (mouse) / Platelet GPIIb |
| Shipping condition: | Room temperature |