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Data sheet of Mouse Monoclonal to beta2-Microglobulin
| Brand | Exbio |
| Product type | Primary antibodies |
| Reactivity | Human |
| Clonality | Monoclonal |
More info about Mouse Monoclonal to beta2-Microglobulin
| Brand: | Exbio |
| Product no.: | 11-237-C025 |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Product name: | Mouse Monoclonal to beta2-Microglobulin |
| Antigen: | beta2-Microglobulin |
| Clonality: | Monoclonal |
| Negative species: | Mouse, Rabbit, Canine (Dog), Chicken, Bovine |
| Clone: | B2M-01 |
| Isotype: | IgG2a |
| Immunogen: | Purified human beta2-microglobulin |
| Format: | purified |
| Specificity: | The antibody B2M-01 reacts with beta2-microglobulin (beta2M) associated with cell-surface MHC Class I molecules and other membrane antigens as well as with soluble beta2-microglobulin. Beta2M is a 12 kDa Ig like glycoprotein expressed on lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells and epithelial cells. It is absent on erythrocytes._x000D_ |
| Categories: | Serum & Plasma Proteins (Human), MHC (Major Histocompatibility Complex) and Related Antigens (Human) |
| Concentration: | 1 mg/ml |
| Storage buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Storage / stability: | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
| Background: | Beta2-microglobulin non-covalently associates with the 44 kDa alpha chain to forms the HLA Class I antigen complex. Human beta2-microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes. |
| Purity: | > 95% (by SDS-PAGE) |
| Purification: | Purified by precipitation methods |
| Product specific references: | *Poláková K, ŽeleznÃková T, Russ G: HLA-G5 in the blood of leukemia patients and healthy individuals. Leuk Res. 2013 Feb;37(2):139-45. , *Lafon M, Prehaud C, Megret F, Lafage M, Mouillot G, Roa M, Moreau P, Rouas-Freiss N, Carosella ED: Modulation of HLA-G Expression in Human Neural Cells after Neurotropic Viral Infections. J Virol. 2005 Dec; 79(24): 15226-15237., *Hilgert I, Horejsi V, Kristofova H: The use of murine monoclonal antibody B2M-01 for detection and purification of_x000D_ human beta 2-microglobulin. Folia Biol (Praha). 1984;30(6):369-76. _x000D_ , *Khurana M, Traum AZ, Aivado M, Wells MP, Guerrero M, Grall F, Libermann TA, Schachter AD: Urine proteomic profiling of pediatric nephrotic syndrome. Pediatr Nephrol. 2006 Sep;21(9):1257-65. Epub 2006 Jun 30. _x000D_ |
| Related products: | - Mouse Monoclonal to beta-Galactosidase - Mouse Monoclonal to beta2-Microglobulin - Mouse Monoclonal to beta-Catenin |
| Shipping condition: | Room temperature |