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Data sheet of HLA-DP monoclonal antibody, clone SPM421
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Clonality | Monoclonal |
| Host species | Mouse |
| Applications | IHC-P,IF,Flow Cyt |
More info about HLA-DP monoclonal antibody, clone SPM421
| Product description: | Mouse monoclonal antibody raised against native human HLA-DP. |
| Clone: | SPM421 |
| Isotype: | IgG2b, kappa |
| Gene id: | 3115 |
| Gene name: | HLA-DPB1 |
| Gene alias: | DPB1|HLA-DP1B |
| Gene description: | major histocompatibility complex, class II, DP beta 1 |
| Immunogen: | Human non-T/non-B-cell-type acute lymphoblastic leukemia REH6 cell line. |
| Protein accession: | P04440 |
| Form: | Liquid |
| Recommend dilutions: | Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In 10 mM PBS (0.05% BSA, 0.05% sodium azide). |
| Storage instruction: | Store at 4°C. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Specificity: | Recognizes a non-polymorphic determinant of DP-MHC class II. MHC class II antigens are transmembrane glycoproteins of non-covalently linked alpha (33-35 kDa) and beta (27-30 kDa) chains. It reportedly reacts with B- & non-T, non-B cell lines but not with T- and myeloid cell lines and leukemias. Differential expression of MHC class II antigens on fetal and adult lymphocytes, malignant B cells appears to reflect the stage of cell differentiation which may be useful in the study of lymphoproliferative disorders. |
| Size: | 100 ug |
| Shipping condition: | Blue Ice |