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Data sheet of PTPRC monoclonal antibody, clone 3G4
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Mouse |
| Applications | ELISA,WB-Ce |
More info about PTPRC monoclonal antibody, clone 3G4
| Brand: | Abnova |
| Reference: | MAB1108 |
| Product name: | PTPRC monoclonal antibody, clone 3G4 |
| Product description: | Mouse monoclonal antibody raised against partial recombinant PTPRC. |
| Clone: | 3G4 |
| Isotype: | IgG2a, kappa |
| Gene id: | 5788 |
| Gene name: | PTPRC |
| Gene alias: | B220|CD45|CD45R|GP180|LCA|LY5|T200 |
| Gene description: | protein tyrosine phosphatase, receptor type, C |
| Genbank accession: | NM_002838 |
| Immunogen: | Recombinant protein corresponding to amino acids 1029-1249 of human PTPRC. |
| Protein accession: | NP_002829 |
| Form: | Liquid |
| Recommend dilutions: | Western Blot (1:1000-1:3000) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS, pH 7.4 (0.09% sodium azide) |
| Storage instruction: | Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Antigen species / target species: | Human |
| Reactivity: | Human |
| Application image: |  |
| Application image note: | Western blot analysis of cell lysates of Jurkat (20 ug) were resolved by SDS - PAGE , transferred to NC membrane and probed with PTPRC monoclonal antibody , clone 3G4 (1 : 2000) (Cat # MAB1108). Proteins were visualized using a goat anti - mouse secondary antibody conjugated to HRP and an ECL detection system. |
| Applications: | ELISA,WB-Ce |
| Shipping condition: | Dry Ice |
| Publications: | Epitope-specific crosslinking of CD45 down-regulates membrane-associated tyrosine phosphatase activity and triggers early signalling events in human activated T cells.Spertini F, Perret-Menoud V, Barbier N, Chatila T, Barbey C, Corthesy B. Immunology. 2004 Dec;113(4):441-52. |