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Data sheet of CRYAB monoclonal antibody, clone 2E8
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human,Mouse |
| Host species | Mouse |
| Applications | ELISA,WB-Re |
More info about CRYAB monoclonal antibody, clone 2E8
| Brand: | Abnova |
| Reference: | MAB1075 |
| Product name: | CRYAB monoclonal antibody, clone 2E8 |
| Product description: | Mouse monoclonal antibody raised against full length recombinant CRYAB. |
| Clone: | 2E8 |
| Isotype: | IgG2b, kappa |
| Gene id: | 1410 |
| Gene name: | CRYAB |
| Gene alias: | CRYA2|CTPP2|HSPB5 |
| Gene description: | crystallin, alpha B |
| Genbank accession: | NM_001885 |
| Immunogen: | Recombinant protein corresponding to full length human CRYAB. |
| Protein accession: | NP_001876 |
| Form: | Liquid |
| Recommend dilutions: | Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS, pH 7.4 (0.09% sodium azide) |
| Storage instruction: | Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Antigen species / target species: | Human |
| Specificity: | This antibody has the specificity against CRYAB, do not detect CRYAA. |
| Reactivity: | Human,Mouse |
| Application image: |  |
| Application image note: | Western blot analysis of recombinant alpha - crystallin A (alphaA) and mouse eye (ME) extract were resolved by SDS - PAGE , transferred to PVDF membrane and probed with CRYAB monoclonal antibody , clone 2E8 (1 : 1000) (Cat # MAB1075) . Proteins were visualized using a goat anti - mouse secondary antibody conjugated to HRP and an ECL detection system. |
| Applications: | ELISA,WB-Re |
| Shipping condition: | Dry Ice |
| Publications: | Inhibition of proteasomes induces accumulation, phosphorylation, and recruitment of HSP27 and alphaB-crystallin to aggresomes.Ito H, Kamei K, Iwamoto I, Inaguma Y, Garcia-Mata R, Sztul E, Kato K. J Biochem. 2002 Apr;131(4):593-603. |