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| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human,Mouse,Rat |
| Host species | Rabbit |
| Applications | ELISA,IHC,WB-Ce |
| Brand: | Abnova |
| Reference: | PAB9992 |
| Product name: | MET (phospho Y1349/1356) polyclonal antibody |
| Product description: | Rabbit polyclonal antibody raised against synthetic phosphopeptide of MET. |
| Gene id: | 4233 |
| Gene name: | MET |
| Gene alias: | AUTS9|HGFR|RCCP2|c-Met |
| Gene description: | met proto-oncogene (hepatocyte growth factor receptor) |
| Immunogen: | Synthetic phosphopeptide corresponding to residues surrounding Y1349/Y1356 of human MET. |
| Protein accession: | NP_000236;P08581 |
| Form: | Liquid |
| Recommend dilutions: | ELISA (1:450000) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01% sodium azide) |
| Storage instruction: | Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Quality control testing: | Antibody Reactive Against Synthetic Peptide. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Rabbit |
| Antigen species / target species: | Human |
| Specificity: | This antibody is specific to human c-Met protein phosphorylated at Y1349 and Y1356. |
| Reactivity: | Human,Mouse,Rat |
| Application image: | ![]() |
| Application image note: | Western blot using MET (phospho Y1349/1356) polyclonal antibody (Cat # PAB9992) shows detection of phosphorylated MET. Human mammary B5/589 epithelial cells were serum-deprived and treated with or without HGF. Cell lysates were immunoprecipated with the anti-MET antibody, resolved by SDS-PAGE, transferred to PVDF membrane, and probed with MET (phospho Y1349/1356) polyclonal antibody (Cat # PAB9992). Personal communication, D. Bottaro and T. Ito, NCI, Bethesda, MD. |
| Applications: | ELISA,IHC,WB-Ce |
| Shipping condition: | Dry Ice |
| Publications: | Receptor tyrosine kinases as therapeutic targets: the model of the MET oncogene.Longati P, Comoglio PM, Bardelli A. Curr Drug Targets. 2001 Mar;2(1):41-55. |