| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human,Mouse,Rat |
| Host species | Rabbit |
| Applications | ELISA,WB-Ce |
| Brand: | Abnova |
| Reference: | PAB7927 |
| Product name: | PTPN6 (phospho S591) polyclonal antibody |
| Product description: | Rabbit polyclonal antibody raised against synthetic phosphopeptide of PTPN6. |
| Gene id: | 5777 |
| Gene name: | PTPN6 |
| Gene alias: | HCP|HCPH|HPTP1C|PTP-1C|SH-PTP1|SHP-1|SHP-1L|SHP1 |
| Gene description: | protein tyrosine phosphatase, non-receptor type 6 |
| Immunogen: | Synthetic phosphopeptide corresponding to residues surrounding S591 of human PTPN6. |
| Form: | Liquid |
| Recommend dilutions: | ELISA (1:2000) Western Blot (1:500) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS (50% glycerol, 1 mg/mL BSA, 0.05% sodium azide) |
| Storage instruction: | Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Quality control testing: | Antibody Reactive Against Synthetic Peptide. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Rabbit |
| Antigen species / target species: | Human |
| Specificity: | The sequence is highly conserved in rat and mouse SHP1. |
| Reactivity: | Human,Mouse,Rat |
| Application image: | ![]() |
| Application image note: | Western blot analysis of human Jurkat cells treated with pervanadate (1 mM) for 30 min (lanes 1 & 2). The blot was exposed to lambda phosphatase (lane 2) and then probed with PTPN6 (phospho S591) polyclonal antibody (Cat # PAB7927). |
| Applications: | ELISA,WB-Ce |
| Shipping condition: | Dry Ice |
| Publications: | Activation of Cdk2 stimulates proteasome-dependent truncation of tyrosine phosphatase SHP-1 in human proliferating intestinal epithelial cells.Simoneau M, Boulanger J, Coulombe G, Renaud MA, Duchesne C, Rivard N. J Biol Chem. 2008 Sep 12;283(37):25544-56. Epub 2008 Jul 10. |