| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human,Mouse,Rat |
| Host species | Rabbit |
| Applications | ELISA,WB-Ce |
| Brand: | Abnova |
| Reference: | PAB7908 |
| Product name: | DOK1 (phospho S450) polyclonal antibody |
| Product description: | Rabbit polyclonal antibody raised against synthetic phosphopeptide of DOK1. |
| Gene id: | 1796 |
| Gene name: | DOK1 |
| Gene alias: | MGC117395|MGC138860|P62DOK |
| Gene description: | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| Immunogen: | Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S450 of human DOK1. |
| Form: | Liquid |
| Recommend dilutions: | ELISA (1:2000) Western Blot (1:500) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS (50% glycerol, 1 mg/mL BSA, 0.05% sodium azide) |
| Storage instruction: | Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Quality control testing: | Antibody Reactive Against Synthetic Peptide. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Rabbit |
| Antigen species / target species: | Human |
| Specificity: | This sequence is conserved in Dok1 from rat (Ser-449) and mouse (Ser-451). The site is not conserved in other Dok family members. |
| Reactivity: | Human,Mouse,Rat |
| Application image: | ![]() |
| Application image note: | Western blot of Jurkat cells stimulated with calyculin A (100 nM, 30 min) (lane 1) followed by lambda phosphatase (lane 2) treatment. The blots were probed with DOK1 (phospho S450) polyclonal antibody (Cat # PAB7908). |
| Applications: | ELISA,WB-Ce |
| Shipping condition: | Dry Ice |
| Publications: | Tyrosine phosphorylation of p62dok by p210bcr-abl inhibits RasGAP activity.Kashige N, Carpino N, Kobayashi R. Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2093-8. |