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Data sheet of APH1A polyclonal antibody
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Goat |
| Applications | ELISA,WB-Ti |
More info about APH1A polyclonal antibody
| Brand: | Abnova |
| Reference: | PAB7304 |
| Product name: | APH1A polyclonal antibody |
| Product description: | Goat polyclonal antibody raised against synthetic peptide of APH1A. |
| Gene id: | 51107 |
| Gene name: | APH1A |
| Gene alias: | 6530402N02Rik|APH-1A|CGI-78 |
| Gene description: | anterior pharynx defective 1 homolog A (C. elegans) |
| Immunogen: | A synthetic peptide corresponding to human APH1A. |
| Immunogen sequence/protein sequence: | C-HVTDRSDARLQYG |
| Protein accession: | NP_001071096.1;NP_057106.2 |
| Form: | Liquid |
| Concentration: | 0.5 mg/mL |
| Recommend dilutions: | ELISA (1:128000) Western Blot (0.05-0.1 ug/mL) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide) |
| Storage instruction: | Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Quality control testing: | Antibody Reactive Against Synthetic Peptide. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Goat |
| Antigen species / target species: | Human |
| Specificity: | This antibody is expected to recognize both reported isoforms (NP_001071096.1 and NP_057106.2). |
| Reactivity: | Human |
| Application image: |  |
| Application image note: | APH1A polyclonal antibody (Cat # PAB7304) (0.05 ug/mL) staining of human brain (cerebral cortex) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. |
| Applications: | ELISA,WB-Ti |
| Shipping condition: | Dry Ice |
| Publications: | Rer1p competes with APH-1 for binding to nicastrin and regulates gamma-secretase complex assembly in the early secretory pathway.Spasic D, Raemaekers T, Dillen K, Declerck I, Baert V, Serneels L, Fullekrug J, Annaert W. J Cell Biol. 2007 Feb 26;176(5):629-40. |