| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Goat |
| Applications | ELISA,WB-Ti |
| Brand: | Abnova |
| Reference: | PAB7236 |
| Product name: | SMN1/SMN2 polyclonal antibody |
| Product description: | Goat polyclonal antibody raised against synthetic peptide of SMN1/SMN2. |
| Gene id: | 6606|6607 |
| Gene name: | SMN1 |
| Gene alias: | BCD541|SMA|SMA1|SMA2|SMA3|SMA4|SMA@|SMN|SMNT|T-BCD541 |
| Gene description: | survival of motor neuron 1, telomeric |
| Immunogen: | A synthetic peptide corresponding to human SMN1, SMN2. |
| Immunogen sequence/protein sequence: | C-DESENSRSPGNKSDN |
| Protein accession: | NP_075012.1 (Gene ID : 6606);NP_000335.1 (Gene ID : 6606);NP_075013.1 (Gene ID : 6607);NP_075014.1 (Gene ID : 6607);NP_075015.1 (Gene ID : 6607);NP_059107.1 (Gene ID : 6607) |
| Form: | Liquid |
| Concentration: | 0.5 mg/mL |
| Recommend dilutions: | ELISA (1:1000) Western Blot (2-4 ug/mL) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide) |
| Storage instruction: | Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Quality control testing: | Antibody Reactive Against Synthetic Peptide. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Goat |
| Antigen species / target species: | Human |
| Specificity: | This antibody is expected to recognize isoforms b and d of SMN1 (NP_075012.1 and NP_000335.1) and all reported isoforms of SMN2 (NP_075013.1, NP_075014.1, NP_075015.1 and NP_059107.1). |
| Reactivity: | Human |
| Application image: | ![]() |
| Application image note: | The SMN1/SMN2 polyclonal antibody (Cat # PAB7236) (2 ug/mL) staining of human brain (cerebellum) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. |
| Applications: | ELISA,WB-Ti |
| Shipping condition: | Dry Ice |
| Publications: | Axonal-SMN (a-SMN), a protein isoform of the survival motor neuron gene, is specifically involved in axonogenesis.Setola V, Terao M, Locatelli D, Bassanini S, Garattini E, Battaglia G. Proc Natl Acad Sci U S A. 2007 Feb 6;104(6):1959-64. Epub 2007 Jan 29. |