| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Goat |
| Applications | ELISA,IHC-P,WB-Tr |
| Brand: | Abnova |
| Reference: | PAB6761 |
| Product name: | PCSK9 polyclonal antibody |
| Product description: | Goat polyclonal antibody raised against synthetic peptide of PCSK9. |
| Gene id: | 255738 |
| Gene name: | PCSK9 |
| Gene alias: | FH3|HCHOLA3|LDLCQ1|NARC-1|NARC1 |
| Gene description: | proprotein convertase subtilisin/kexin type 9 |
| Immunogen: | A synthetic peptide corresponding to C-terminus of human PCSK9. |
| Immunogen sequence/protein sequence: | CRSRHLAQASQELQ |
| Protein accession: | NP_777596.2 |
| Form: | Liquid |
| Concentration: | 0.5 mg/mL |
| Recommend dilutions: | ELISA (1:16000) Western Blot (0.3 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2-6 ug/mL) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide) |
| Storage instruction: | Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Goat |
| Antigen species / target species: | Human |
| Reactivity: | Human |
| Application image: | ![]() |
| Application image note: | PCSK9 polyclonal antibody (Cat # PAB6761) staining (0.2 ug/mL) of McA cell lysates: untransfected (Lane 1), transfected with wild type human PCSK9 (Lane 2), transfected with S127R human PCSK9 (Lane 3). Data kindly provided by Dr. X-M Sun, Hammersmith Hospital, London. |
| Applications: | ELISA,IHC-P,WB-Tr |
| Shipping condition: | Dry Ice |
| Publications: | Evidence for effect of mutant PCSK9 on apolipoprotein B secretion as the cause of unusually severe dominant hypercholesterolaemia.Sun XM, Eden ER, Tosi I, Neuwirth CK, Wile D, Naoumova RP, Soutar AK. Hum Mol Genet. 2005 May 1;14(9):1161-9. Epub 2005 Mar 16. |