| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Goat |
| Applications | ELISA,IHC-P |
| Brand: | Abnova |
| Reference: | PAB6354 |
| Product name: | ALMS1 polyclonal antibody |
| Product description: | Goat polyclonal antibody raised against synthetic peptide of ALMS1. |
| Gene id: | 7840 |
| Gene name: | ALMS1 |
| Gene alias: | ALSS|DKFZp686A118|DKFZp686D1828|KIAA0328 |
| Gene description: | Alstrom syndrome 1 |
| Immunogen: | A synthetic peptide corresponding to human ALMS1. |
| Immunogen sequence/protein sequence: | C-RVTNQLLGRKVPWD |
| Protein accession: | NP_055935.3 |
| Form: | Liquid |
| Concentration: | 0.5 mg/mL |
| Recommend dilutions: | ELISA (1:32000) Immunohistochemistry (1-3 ug/mL) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide) |
| Storage instruction: | Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Quality control testing: | Antibody Reactive Against Synthetic Peptide. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Goat |
| Antigen species / target species: | Human |
| Specificity: | The C terminus of ALMS1 shares an 8 amino acid stretch with two other human proteins: hypothetical protein (XP_169104) and ERAL1 (NP_005693). However, this stretch is located internally in these two proteins and so will most likely not cross-react with this antibody. The N terminus was not chosen as the peptide is expected to cyclise during synthesis. |
| Reactivity: | Human |
| Application image: | ![]() |
| Application image note: | ALMS1 polyclonal antibody (Cat # PAB6354) staining (2 ug/mL) of paraffin embedded human testis. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining. |
| Applications: | ELISA,IHC-P |
| Shipping condition: | Dry Ice |
| Publications: | Mutations in ALMS1 cause obesity, type 2 diabetes and neurosensory degeneration in Alstrom syndrome.Collin GB, Marshall JD, Ikeda A, So WV, Russell-Eggitt I, Maffei P, Beck S, Boerkoel CF, Sicolo N, Martin M, Nishina PM, Naggert JK. Nat Genet. 2002 May;31(1):74-8. Epub 2002 Apr 8. |