| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human,Mouse |
| Host species | Rabbit |
| Applications | ELISA,IHC-P,WB-Tr,Flow Cyt |
| Brand: | Abnova |
| Reference: | PAB4898 |
| Product name: | APP polyclonal antibody |
| Product description: | Rabbit polyclonal antibody raised against synthetic peptide of APP. |
| Gene id: | 351 |
| Gene name: | APP |
| Gene alias: | AAA|ABETA|ABPP|AD1|APPI|CTFgamma|CVAP|PN2 |
| Gene description: | amyloid beta (A4) precursor protein |
| Immunogen: | A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human APP. |
| Protein accession: | A4_HUMAN |
| Form: | Liquid |
| Recommend dilutions: | ELISA (1:1000) Western Blot (1:50-100) Immunohistochemistry (1:10-50) Flow cytometry (1:10-50) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS (0.09% sodium azide) |
| Storage instruction: | Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Rabbit |
| Antigen species / target species: | Human |
| Reactivity: | Human,Mouse |
| Application image: | ![]() |
| Application image note: | Western blot analysis of APP (arrow) using rabbit APP polyclonal antibody (Cat # PAB4898). 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the APP gene (Lane 2) (Origene Technologies). |
| Applications: | ELISA,IHC-P,WB-Tr,Flow Cyt |
| Shipping condition: | Dry Ice |
| Publications: | Notch1 competes with the amyloid precursor protein for gamma-secretase and down-regulates presenilin-1 gene expression.Lleo A, Berezovska O, Ramdya P, Fukumoto H, Raju S, Shah T, Hyman BT. J Biol Chem. 2003 Nov 28;278(48):47370-5. Epub 2003 Sep 5. |