| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Rabbit |
| Applications | ELISA,WB-Ce,IHC-P |
| Brand: | Abnova |
| Reference: | PAB4446 |
| Product name: | TSC2 polyclonal antibody |
| Product description: | Rabbit polyclonal antibody raised against synthetic peptide of TSC2. |
| Gene id: | 7249 |
| Gene name: | TSC2 |
| Gene alias: | FLJ43106|LAM|TSC4 |
| Gene description: | tuberous sclerosis 2 |
| Immunogen: | A synthetic peptide (conjugated with KLH) corresponding to residues surrounding S1798 of human TSC2. |
| Protein accession: | NP_000539;P49815 |
| Form: | Liquid |
| Recommend dilutions: | ELISA (1:1000) Western Blot (1:50-100) Immunohistochemistry (1:10-50) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS (0.09% sodium azide) |
| Storage instruction: | Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Rabbit |
| Antigen species / target species: | Human |
| Reactivity: | Human |
| Application image: | ![]() |
| Application image note: | Formalin-fixed and paraffin-embedded human hepatocellular carcinoma reacted with TSC2 polyclonal antibody (Cat # PAB4446) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated . |
| Applications: | ELISA,WB-Ce,IHC-P |
| Shipping condition: | Dry Ice |
| Publications: | Regulation of B-Raf kinase activity by tuberin and Rheb is mammalian target of rapamycin (mTOR)-independent.Karbowniczek M, Cash T, Cheung M, Robertson GP, Astrinidis A, Henske EP. J Biol Chem. 2004 Jul 16;279(29):29930-7. Epub 2004 May 18. |