Brand | Abnova |
Product type | Primary antibodies |
Reactivity | Human |
Host species | Rabbit |
Applications | WB-Ce,IHC-P |
Brand: | Abnova |
Reference: | PAB3646 |
Product name: | SIGLEC11 polyclonal antibody |
Product description: | Rabbit polyclonal antibody raised against synthetic peptide of SIGLEC11. |
Gene id: | 114132 |
Gene name: | SIGLEC11 |
Gene alias: | - |
Gene description: | sialic acid binding Ig-like lectin 11 |
Immunogen: | A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human SIGLEC11. |
Protein accession: | AAK72907 |
Form: | Liquid |
Recommend dilutions: | Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:10-50) Western Blot (1:1000) The optimal working dilution should be determined by the end user. |
Storage buffer: | In PBS (0.09% sodium azide) |
Storage instruction: | Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Product type: | Primary antibodies |
Host species: | Rabbit |
Antigen species / target species: | Human |
Reactivity: | Human |
Application image: | ![]() |
Application image note: | Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with SIGLEC11 polyclonal antibody (Cat # PAB3646) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma. |
Applications: | WB-Ce,IHC-P |
Shipping condition: | Dry Ice |
Publications: | Cloning and characterization of human Siglec-11. A recently evolved signaling molecule that can interact with SHP-1 and SHP-2 and is expressed by tissue macrophages, including brain microglia.Angata T, Kerr SC, Greaves DR, Varki NM, Crocker PR, Varki A. J Biol Chem. 2002 Jul 5;277(27):24466-74. Epub 2002 May 1. |