| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human,Mouse |
| Host species | Rabbit |
| Applications | WB-Ti,IHC-P |
| Brand: | Abnova |
| Reference: | PAB2450 |
| Product name: | BAD polyclonal antibody |
| Product description: | Rabbit polyclonal antibody raised against synthetic peptide of BAD. |
| Gene id: | 572 |
| Gene name: | BAD |
| Gene alias: | BBC2|BCL2L8 |
| Gene description: | BCL2-associated agonist of cell death |
| Immunogen: | A synthetic peptide (conjugated with KLH) corresponding to amino acids 100-130 of human BAD. |
| Protein accession: | NP_116784;Q92934 |
| Form: | Liquid |
| Recommend dilutions: | Western Blot (1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS (0.09% sodium azide) |
| Storage instruction: | Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Rabbit |
| Antigen species / target species: | Human |
| Reactivity: | Human,Mouse |
| Application image: | ![]() |
| Application image note: | Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with the BAD polyclonal antibody (Cat # PAB2450) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma. |
| Applications: | WB-Ti,IHC-P |
| Shipping condition: | Dry Ice |
| Publications: | Inhibition of phosphorylation of BAD and Raf-1 by Akt sensitizes human ovarian cancer cells to paclitaxel.Mabuchi S, Ohmichi M, Kimura A, Hisamoto K, Hayakawa J, Nishio Y, Adachi K, Takahashi K, Arimoto-Ishida E, Nakatsuji Y, Tasaka K, Murata Y. J Biol Chem. 2002 Sep 6;277(36):33490-500. Epub 2002 Jun 26. |