| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Rabbit |
| Applications | WB-Ti,IHC-P |
| Brand: | Abnova |
| Reference: | PAB2022 |
| Product name: | ACVR2B polyclonal antibody |
| Product description: | Rabbit polyclonal antibody raised against synthetic peptide of ACVR2B. |
| Gene id: | 93 |
| Gene name: | ACVR2B |
| Gene alias: | ACTRIIB|ActR-IIB|MGC116908 |
| Gene description: | activin A receptor, type IIB |
| Immunogen: | A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human ACVR2B. |
| Protein accession: | NP_001097;Q13705 |
| Form: | Liquid |
| Recommend dilutions: | Western Blot (1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS (0.09% sodium azide) |
| Storage instruction: | Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Rabbit |
| Antigen species / target species: | Human |
| Reactivity: | Human |
| Application image: | ![]() |
| Application image note: | Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with ACVR2B polyclonal antibody (Cat # PAB2022) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma. |
| Applications: | WB-Ti,IHC-P |
| Shipping condition: | Dry Ice |
| Publications: | Modulation of noncanonical TGF-β signaling prevents cleft palate in Tgfbr2 mutant mice.Iwata J, Hacia JG, Suzuki A, Sanchez-Lara PA, Urata M, Chai Y. J Clin Invest. 2012 Mar 1;122(3):873-85. doi: 10.1172/JCI61498. Epub 2012 Feb 13. |