| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Rabbit |
| Applications | IHC-P,WB-Tr |
| Brand: | Abnova |
| Reference: | PAB1988 |
| Product name: | MTOR polyclonal antibody |
| Product description: | Rabbit polyclonal antibody raised against synthetic peptide of FRAP1. |
| Gene id: | 2475 |
| Gene name: | MTOR |
| Gene alias: | FRAP|FRAP1|FRAP2|RAFT1|RAPT1 |
| Gene description: | mechanistic target of rapamycin |
| Immunogen: | A synthetic peptide (conjugated with KLH) corresponding to residues surrounding S2481 of human FRAP1. |
| Protein accession: | NP_004949;P42345 |
| Form: | Liquid |
| Recommend dilutions: | Western Blot (1:1000) Immunohistochemistry (1:10-50) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS (0.09% sodium azide) |
| Storage instruction: | Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Rabbit |
| Antigen species / target species: | Human |
| Reactivity: | Human |
| Application image: | ![]() |
| Application image note: | Formalin-fixed and paraffin-embedded human testis tissue reacted with MTOR polyclonal antibody (Cat # PAB1988) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
| Applications: | IHC-P,WB-Tr |
| Shipping condition: | Dry Ice |
| Publications: | Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells.Dowling RJ, Zakikhani M, Fantus IG, Pollak M, Sonenberg N. Cancer Res. 2007 Nov 15;67(22):10804-12. |