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Data sheet of ACAN polyclonal antibody
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human,Rat |
| Host species | Rabbit |
| Applications | ELISA,IHC,WB-Ce,IHC-P |
More info about ACAN polyclonal antibody
| Brand: | Abnova |
| Reference: | PAB18067 |
| Product name: | ACAN polyclonal antibody |
| Product description: | Rabbit polyclonal antibody raised against synthetic peptide of ACAN . |
| Gene id: | 176 |
| Gene name: | ACAN |
| Gene alias: | AGC1|AGCAN|CSPG1|CSPGCP|MSK16|SEDK |
| Gene description: | aggrecan |
| Immunogen: | A synthetic peptide corresponding to amino acids 336-369 of human ACAN. |
| Immunogen sequence/protein sequence: | FFGVGGEED |
| Protein accession: | P16112 |
| Form: | Liquid |
| Recommend dilutions: | Western Blot (1:500~1:1000) Immunohistochemistry (1:50~1:100) ELISA(1:20000) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide) |
| Storage instruction: | Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Rabbit |
| Antigen species / target species: | Human |
| Specificity: | This antibody is specific to endogenous levels of fragment of activated ACAN resulting from cleavage adjacent to Asp369. |
| Reactivity: | Human,Rat |
| Application image: |  |
| Application image note: | Western blot analysis of extracts from Jurkat cells, treated with Etoposide (25 uM, 60 mins), using ACAN polyclonal antibody (Cat # PAB18067). Peptide "+" means "with peptide blocking". |
| Applications: | ELISA,IHC,WB-Ce,IHC-P |
| Shipping condition: | Dry Ice |
| Publications: | SOX9 enhances aggrecan gene promoter/enhancer activity and is up-regulated by retinoic acid in a cartilage-derived cell line, TC6.Sekiya I, Tsuji K, Koopman P, Watanabe H, Yamada Y, Shinomiya K, Nifuji A, Noda M. J Biol Chem. 2000 Apr 14;275(15):10738-44. |