| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human,Mouse |
| Host species | Rabbit |
| Applications | WB-Ce,IHC-P,IF |
| Brand: | Abnova |
| Reference: | PAB1748 |
| Product name: | SMURF2 polyclonal antibody |
| Product description: | Rabbit polyclonal antibody raised against synthetic peptide of SMURF2. |
| Gene id: | 64750 |
| Gene name: | SMURF2 |
| Gene alias: | DKFZp686F0270|MGC138150 |
| Gene description: | SMAD specific E3 ubiquitin protein ligase 2 |
| Immunogen: | A synthetic peptide (conjugated with KLH) corresponding to amino acids 702-731 of human SMURF2. |
| Protein accession: | Q9HAU4 |
| Form: | Liquid |
| Recommend dilutions: | Immnunofluorescence (1:10-1:50) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100) Western Blot (1:1000) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS (0.09% sodium azide) |
| Storage instruction: | Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Rabbit |
| Antigen species / target species: | Human |
| Reactivity: | Human,Mouse |
| Application image: | ![]() |
| Application image note: | Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with SMURF2 polyclonal antibody (Cat # PAB1748) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. HC = hepatocarcinoma. |
| Applications: | WB-Ce,IHC-P,IF |
| Shipping condition: | Dry Ice |
| Publications: | The interaction of mPar3 with the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity.Schwamborn JC, Khazaei MR, Puschel AW. J Biol Chem. 2007 Nov 30;282(48):35259-68. Epub 2007 Sep 28. |