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Data sheet of SMURF1 polyclonal antibody
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human,Mouse |
| Host species | Rabbit |
| Applications | WB,WB-Ti,IHC-P |
More info about SMURF1 polyclonal antibody
| Brand: | Abnova |
| Reference: | PAB1747 |
| Product name: | SMURF1 polyclonal antibody |
| Product description: | Rabbit polyclonal antibody raised against synthetic peptide of SMURF1. |
| Gene id: | 57154 |
| Gene name: | SMURF1 |
| Gene alias: | KIAA1625 |
| Gene description: | SMAD specific E3 ubiquitin protein ligase 1 |
| Immunogen: | A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human SMURF1. |
| Protein accession: | NP_065162;Q9HCE7 |
| Form: | Liquid |
| Recommend dilutions: | Western Blot (1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS (0.09% sodium azide) |
| Storage instruction: | Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Rabbit |
| Antigen species / target species: | Human |
| Reactivity: | Human,Mouse |
| Application image: |  |
| Application image note: | Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with SMURF1 polyclonal antibody (Cat # PAB1747) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
| Applications: | WB,WB-Ti,IHC-P |
| Shipping condition: | Dry Ice |
| Publications: | Tumor necrosis factor promotes Runx2 degradation through up-regulation of Smurf1 and Smurf2 in osteoblasts.Kaneki H, Guo R, Chen D, Yao Z, Schwarz EM, Zhang YE, Boyce BF, Xing L. J Biol Chem. 2006 Feb 17;281(7):4326-33. Epub 2005 Dec 22. |