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Data sheet of IRS1 (phospho S176) polyclonal antibody
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human,Mouse,Rat |
| Host species | Rabbit |
| Applications | WB,ELISA,IHC-P |
More info about IRS1 (phospho S176) polyclonal antibody
| Brand: | Abnova |
| Reference: | PAB16977 |
| Product name: | IRS1 (phospho S176) polyclonal antibody |
| Product description: | Rabbit polyclonal antibody raised against synthetic phosphopeptide of IRS1. |
| Gene id: | 3667 |
| Gene name: | IRS1 |
| Gene alias: | HIRS-1 |
| Gene description: | insulin receptor substrate 1 |
| Immunogen: | Synthetic phosphopeptide corresponding to residues surrounding S176 of human IRS1. |
| Protein accession: | P35569 |
| Form: | Liquid |
| Recommend dilutions: | Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:4000) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In 20 mM PBS, 0.15 M NaCl, pH 7.2 (0.01% sodium azide) |
| Storage instruction: | Store at 4°C for three months. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Rabbit |
| Antigen species / target species: | Human |
| Specificity: | This antibody detects endogenous levels of IRS1 only when phosphorylated at serine 612. |
| Reactivity: | Human,Mouse,Rat |
| Application image: |  |
| Application image note: | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IRS1 (phospho Ser176) polyclonal antibody (Cat # PAB16977). |
| Applications: | WB,ELISA,IHC-P |
| Shipping condition: | Dry Ice |
| Publications: | Tyr(612) and Tyr(632) in human insulin receptor substrate-1 are important for full activation of insulin-stimulated phosphatidylinositol 3-kinase activity and translocation of GLUT4 in adipose cells.Esposito DL, Li Y, Cama A, Quon MJ. Endocrinology. 2001 Jul;142(7):2833-40. |