| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Goat |
| Applications | ELISA,WB-Ti,IHC-P |
| Brand: | Abnova |
| Reference: | PAB16250 |
| Product name: | P2RX7 polyclonal antibody |
| Product description: | Goat polyclonal antibody raised against synthetic peptide of P2RX7. |
| Gene id: | 5027 |
| Gene name: | P2RX7 |
| Gene alias: | MGC20089|P2X7 |
| Gene description: | purinergic receptor P2X, ligand-gated ion channel, 7 |
| Immunogen: | A synthetic peptide corresponding to N-terminus of human P2RX7. |
| Immunogen sequence/protein sequence: | YETNKVTRIQSMNY-C |
| Protein accession: | NP_002553.2 |
| Form: | Liquid |
| Concentration: | 0.5 mg/mL |
| Recommend dilutions: | ELISA (1:16000) Western Blot (1-3 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (3-6 ug/mL) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide) |
| Storage instruction: | Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Goat |
| Antigen species / target species: | Human |
| Reactivity: | Human |
| Application image: | ![]() |
| Application image note: | P2RX7 polyclonal antibody (Cat # PAB16250) staining (0.3 ug/mL) of human brain (frontal cortex) lysate (35 ug protein in RIPA buffer) with (Lane 2) and without (Lane 1) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence. |
| Applications: | ELISA,WB-Ti,IHC-P |
| Shipping condition: | Dry Ice |
| Publications: | Activated microglia in ischemic stroke penumbra upregulate MCP-1 and CCR2 expression in response to lysophosphatidylcholine derived from adjacent neurons and astrocytes.Inose Y, Kato Y, Kitagawa K, Uchiyama S, Shibata N Neuropathology. 2014 Dec 2. doi: 10.1111/neup.12182. |