| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Goat |
| Applications | ELISA,WB-Ce |
| Brand: | Abnova |
| Reference: | PAB14389 |
| Product name: | CYBB polyclonal antibody |
| Product description: | Goat polyclonal antibody raised against synthetic peptide of CYBB. |
| Gene id: | 1536 |
| Gene name: | CYBB |
| Gene alias: | CGD|GP91-1|GP91-PHOX|GP91PHOX|NOX2|p91-PHOX |
| Gene description: | cytochrome b-245, beta polypeptide |
| Immunogen: | A synthetic peptide corresponding to human CYBB. |
| Immunogen sequence/protein sequence: | C-SYLNFARKRIKNP |
| Protein accession: | NP_000388.2 |
| Form: | Liquid |
| Concentration: | 0.5 mg/mL |
| Recommend dilutions: | ELISA (1:2000) Western Blot (0.03-0.1 ug/mL) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide) |
| Storage instruction: | Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Goat |
| Antigen species / target species: | Human |
| Specificity: | Approx 85 KDa band observed in human peripheral blood mononucleocytes ysates (calculated MW of 65.3KDa according to NP_000388.2). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Teahan et al, Nature. 1987 Jun 25-Jul 1;327(6124):720-1. PMID: 3600769). |
| Reactivity: | Human |
| Application image: | ![]() |
| Application image note: | CYBB polyclonal antibody (Cat # PAB14389) (0.03 ug/mL) staining of human peripheral blood mononucleocyte lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. |
| Applications: | ELISA,WB-Ce |
| Shipping condition: | Dry Ice |
| Publications: | Constitutive activation of SHP2 protein tyrosine phosphatase inhibits ICSBP-induced transcription of the gene encoding gp91PHOX during myeloid differentiation.Zhu C, Lindsey S, Konieczna I, Eklund EA. J Leukoc Biol. 2008 Mar;83(3):680-91. Epub 2007 Dec 18. |