| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Rabbit |
| Applications | IP,ELISA,IHC,Dot-Pep,WB-Ti |
| Brand: | Abnova |
| Reference: | PAB12749 |
| Product name: | JAK2 (phospho Y1007/Y1008) polyclonal antibody |
| Product description: | Rabbit polyclonal antibody raised against synthetic phosphopeptide of JAK2. |
| Gene id: | 3717 |
| Gene name: | JAK2 |
| Gene alias: | JTK10 |
| Gene description: | Janus kinase 2 (a protein tyrosine kinase) |
| Immunogen: | Synthetic phosphopeptide corresponding to residues surrounding Y1007/Y1008 of human, mouse and rat JAK2. |
| Immunogen sequence/protein sequence: | EYYK |
| Form: | Liquid |
| Recommend dilutions: | Western Blot (0.1-1 ug/mL) ELISA (0.01-0.1 ug/mL) Immunoprecipitation (2-5 ug/mL) Immunohistochemistry (1-5 ug/mL) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In TBS, pH 7.2 (BSA, 10% Proclin300) |
| Storage instruction: | Store at -20°C. For long term storage store at -80°C. Aliquot to avoid repeated freezing and thawing. |
| Quality control testing: | Antibody Reactive Against Synthetic Peptide. |
| Product type: | Primary antibodies |
| Host species: | Rabbit |
| Antigen species / target species: | Human,Mouse,Rat |
| Specificity: | This antibody recognizes JAK2 with dual phosphorylated sites of Tyr1007/1008. It does not cross-react with non-phosphospecific peptide. |
| Reactivity: | Human |
| Application image: | ![]() |
| Application image note: | The tissue lysate derived from GH stimulated mouse liver was immunoblotted by JAK2 (phospho Y1007/Y1008) polyclonal antibody (Cat # PAB12749) at 1 : 500. |
| Applications: | IP,ELISA,IHC,Dot-Pep,WB-Ti |
| Shipping condition: | Dry Ice |
| Publications: | SHP-2 regulates SOCS-1-mediated Janus kinase-2 ubiquitination/degradation downstream of the prolactin receptor.Ali S, Nouhi Z, Chughtai N, Ali S. J Biol Chem. 2003 Dec 26;278(52):52021-31. Epub 2003 Oct 1. |