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Data sheet of Kdr polyclonal antibody
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human,Mouse,Rat |
| Host species | Rabbit |
| Applications | WB-Tr,Flow Cyt |
More info about Kdr polyclonal antibody
| Brand: | Abnova |
| Reference: | PAB12134 |
| Product name: | Kdr polyclonal antibody |
| Product description: | Rabbit polyclonal antibody raised against synthetic peptide of Kdr. |
| Gene id: | 16542 |
| Gene name: | Kdr |
| Gene alias: | 6130401C07|Flk-1|Flk1|Krd-1|Ly73|VEGFR-2|VEGFR2 |
| Gene description: | kinase insert domain protein receptor |
| Immunogen: | A synthetic peptide corresponding to amino acids 1300-1367 of mouse Kdr. |
| Protein accession: | P35918 |
| Form: | Liquid |
| Recommend dilutions: | Flow Cytometry (1:100) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In Tris-citrate/phosphate buffer, pH 7.0-8.0 (0.09% sodium azide) |
| Storage instruction: | Store at 4°C. Do not freeze. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Rabbit |
| Antigen species / target species: | Mouse |
| Specificity: | This antibody has only been shown to recognize the native form (180-190 KDa protein) of VEGFR-2, known as Flk-1 / KDR / VEGFR 2 (Vascular Endothelial Growth Factor Receptor 2), though it was raised against the precursor form. It has not been characterized against the other forms of VEGFR-2. It has not been tested for cross-reactivity with VEGFR-1. |
| Reactivity: | Human,Mouse,Rat |
| Application image: |  |
| Application image note: | Western blot analysis of Kdr in CSF-IR/VEGFR2 chimera transfected lysate using Kdr polyclonal antibody (Cat # PAB12134). ECL 10 second exposure. |
| Applications: | WB-Tr,Flow Cyt |
| Shipping condition: | Blue Ice |
| Publications: | Nonclinical antiangiogenesis and antitumor activities of axitinib (AG-013736), an oral, potent, and selective inhibitor of vascular endothelial growth factor receptor tyrosine kinases 1, 2, 3.Hu-Lowe DD, Zou HY, Grazzini ML, Hallin ME, Wickman GR, Amundson K, Chen JH, Rewolinski DA, Yamazaki S, Wu EY, McTigue MA, Murray BW, Kania RS, O'Connor P, Shalinsky DR, Bender SL. Clin Cancer Res. 2008 Nov 15;14(22):7272-83. |