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Data sheet of DES polyclonal antibody
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human,Mouse,Rat |
| Host species | Goat |
| Applications | ELISA,WB-Ti,IHC-P |
More info about DES polyclonal antibody
| Brand: | Abnova |
| Reference: | PAB11453 |
| Product name: | DES polyclonal antibody |
| Product description: | Goat polyclonal antibody raised against synthetic peptide of DES. |
| Gene id: | 1674 |
| Gene name: | DES |
| Gene alias: | CMD1I|CSM1|CSM2|FLJ12025|FLJ39719|FLJ41013|FLJ41793 |
| Gene description: | desmin |
| Immunogen: | A synthetic peptide corresponding to C-terminus of human DES. |
| Immunogen sequence/protein sequence: | C-RDGEVVSEATQQQHE |
| Protein accession: | NP_001918.3 |
| Form: | Liquid |
| Concentration: | 0.5 mg/mL |
| Recommend dilutions: | ELISA (1:2000) Western Blot (0.1-0.3 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (3-6 ug/mL) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide) |
| Storage instruction: | Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Goat |
| Antigen species / target species: | Human |
| Reactivity: | Human,Mouse,Rat |
| Application image: |  |
| Application image note: | DES polyclonal antibody (Cat # PAB11453) (0.2 ug/mL) staining of human skeletal muscle lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. |
| Applications: | ELISA,WB-Ti,IHC-P |
| Shipping condition: | Dry Ice |
| Publications: | Caspase proteolysis of desmin produces a dominant-negative inhibitor of intermediate filaments and promotes apoptosis.Chen F, Chang R, Trivedi M, Capetanaki Y, Cryns VL. J Biol Chem. 2003 Feb 28;278(9):6848-53. Epub 2002 Dec 10. |