| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Chicken,Chimpanzee,Human,Pig |
| Host species | Rabbit |
| Applications | WB,ELISA,IHC |
| Brand: | Abnova |
| Reference: | PAB10327 |
| Product name: | HTT (phospho S421) polyclonal antibody |
| Product description: | Rabbit polyclonal antibody raised against synthetic phosphopeptide of HTT. |
| Gene id: | 3064 |
| Gene name: | HTT |
| Gene alias: | HD|IT15 |
| Gene description: | huntingtin |
| Immunogen: | Synthetic phosphopeptide corresponding to residues surrounding S421 of human HTT. |
| Protein accession: | P42858;NP_002102 |
| Form: | Liquid |
| Recommend dilutions: | ELISA (1:10000-1:40000) Western Blot (1:500-1:3000) Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01% sodium azide) |
| Storage instruction: | Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Quality control testing: | Antibody Reactive Against Synthetic Peptide. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Rabbit |
| Antigen species / target species: | Human |
| Specificity: | This antibody is specific to phosphorylated human Huntingtin protein at the pS421 residue. Minimal reactivity isexpected with the non-phosphorylated form of the protein. |
| Reactivity: | Chicken,Chimpanzee,Human,Pig |
| Applications: | WB,ELISA,IHC |
| Shipping condition: | Dry Ice |
| Publications: | Calmodulin regulates transglutaminase 2 cross-linking of huntingtin.Zainelli GM, Ross CA, Troncoso JC, Fitzgerald JK, Muma NA. J Neurosci. 2004 Feb 25;24(8):1954-61. |