| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Rabbit |
| Applications | WB,ELISA,IHC-P |
| Brand: | Abnova |
| Reference: | PAB10292 |
| Product name: | NOTCH1 polyclonal antibody |
| Product description: | Rabbit polyclonal antibody raised against synthetic peptide of NOTCH1. |
| Gene id: | 4851 |
| Gene name: | NOTCH1 |
| Gene alias: | TAN1|hN1 |
| Gene description: | Notch homolog 1, translocation-associated (Drosophila) |
| Immunogen: | A synthetic peptide corresponding to amino acids 2488-2502 of human NOTCH1. |
| Immunogen sequence/protein sequence: | CQHSYSSPVDNTPSHQ |
| Protein accession: | P46531 (human) |
| Form: | Liquid |
| Recommend dilutions: | ELISA (1:20000-1:100000) Western Blot (1:2000-1:10000) Immunohistochemistry (1:1000-1:5000) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01% sodium azide) |
| Storage instruction: | Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Quality control testing: | Antibody Reactive Against Synthetic Peptide. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Rabbit |
| Antigen species / target species: | Human |
| Specificity: | This antiserum is directed against human NOTCH 1. No reaction is detected against NOTCH 2. No reactivity was observed against Mouse Notch. |
| Reactivity: | Human |
| Application image: | ![]() |
| Application image note: | Immunohistochemical staining with NOTCH1 polyclonal antibody (Cat # PAB10292) was diluted 1 : 500 to detect NOTCH 1 in human brain cerebellum tissue. Tissue was formalin fixed and paraffin embedded. No pre-treatment of sample was required. The image shows the localization of antibody as the precipitated red signal, with a hematoxylin purple nuclear counter stain. |
| Applications: | WB,ELISA,IHC-P |
| Shipping condition: | Dry Ice |
| Publications: | Notch-1 and Notch-2 exhibit unique patterns of expression in human B-lineage cells.Bertrand FE, Eckfeldt CE, Lysholm AS, LeBien TW. Leukemia. 2000 Dec;14(12):2095-102. |