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Data sheet of CRTC1 polyclonal antibody
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Bovine,Human,Mouse,Pufferfishes,Rat |
| Host species | Rabbit |
| Applications | WB,ELISA |
More info about CRTC1 polyclonal antibody
| Brand: | Abnova |
| Reference: | PAB10265 |
| Product name: | CRTC1 polyclonal antibody |
| Product description: | Rabbit polyclonal antibody raised against synthetic peptide of CRTC1. |
| Gene id: | 23373 |
| Gene name: | CRTC1 |
| Gene alias: | FLJ14027|KIAA0616|MECT1|TORC1|WAMTP1 |
| Gene description: | CREB regulated transcription coactivator 1 |
| Immunogen: | A synthetic peptide corresponding to amino acids 19-34 of human CRTC1. |
| Protein accession: | NP_056136(isoform1);Q6UUV9 |
| Form: | Liquid |
| Recommend dilutions: | ELISA (1:10000-1:40000) Western Blot (1:500-1:20000 The optimal working dilution should be determined by the end user. |
| Storage buffer: | In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01% sodium azide) |
| Storage instruction: | Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Quality control testing: | Antibody Reactive Against Synthetic Peptide. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Rabbit |
| Antigen species / target species: | Human |
| Specificity: | This affinity-purified antibody is directed against human MECT1 protein. |
| Reactivity: | Bovine,Human,Mouse,Pufferfishes,Rat |
| Application image: |  |
| Application image note: | Western blot using CRTC1 polyclonal antibody (Cat # PAB10265) shows detection of CRTC1 (lower arrowhead) and CRTC1 : MAML2 fusion protein (top arrowhead) in cell lysates. Lane 1 contains lysate from cells expressing CRTC1 only. Lane 2 contains lysate from cells transfected with fusion protein. Lane 3 contains lysate from cells strongly expressing CRTC1 and weakly expressing the fusion protein. Lane 4 contains lysate from control cells. After SDS-PAGE and transfer, the membrane was probed with the primary antibody diluted to 1:1,000. Personal Communication, Frederick Kaye, CCR-NCI, Bethesda, MD. |
| Applications: | WB,ELISA |
| Shipping condition: | Dry Ice |
| Publications: | t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway.Tonon G, Modi S, Wu L, Kubo A, Coxon AB, Komiya T, O'Neil K, Stover K, El-Naggar A, Griffin JD, Kirsch IR, Kaye FJ. Nat Genet. 2003 Feb;33(2):208-13. Epub 2003 Jan 21. |