| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Rabbit |
| Applications | WB-Ce |
| Brand: | Abnova |
| Reference: | PAB0408 |
| Product name: | APP (phospho S730) polyclonal antibody |
| Product description: | Rabbit polyclonal antibody raised against synthetic phosphopeptide of APP. |
| Gene id: | 351 |
| Gene name: | APP |
| Gene alias: | AAA|ABETA|ABPP|AD1|APPI|CTFgamma|CVAP|PN2 |
| Gene description: | amyloid beta (A4) precursor protein |
| Immunogen: | Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S730 of human APP. |
| Protein accession: | NP_000475;P05067 |
| Form: | Liquid |
| Recommend dilutions: | Western Blot (1:1000) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS (0.09% sodium azide) |
| Storage instruction: | Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Rabbit |
| Antigen species / target species: | Human |
| Reactivity: | Human |
| Application image: | ![]() |
| Application image note: | The APP (phospho S730) polyclonal antibody (Cat # PAB0408) is used in Western blot to detect Phospho-APP-S730 in Jurkat cell lysate. |
| Applications: | WB-Ce |
| Shipping condition: | Dry Ice |
| Publications: | Notch1 competes with the amyloid precursor protein for gamma-secretase and down-regulates presenilin-1 gene expression.Lleo A, Berezovska O, Ramdya P, Fukumoto H, Raju S, Shah T, Hyman BT. J Biol Chem. 2003 Nov 28;278(48):47370-5. Epub 2003 Sep 5. |