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| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Mouse |
| Applications | IHC,WB-Ti |
| Brand: | Abnova |
| Reference: | MAB8817 |
| Product name: | MBP monoclonal antibody, clone QD-9 |
| Product description: | Mouse monoclonal antibody raised against synthetic peptide of MBP. |
| Clone: | QD-9 |
| Isotype: | IgG |
| Gene id: | 4155 |
| Gene name: | MBP |
| Gene alias: | MGC99675 |
| Gene description: | myelin basic protein |
| Immunogen: | A synthetic peptide corresponding to amino acids 215-221 of human MBP. |
| Immunogen sequence/protein sequence: | QDENPVV |
| Form: | Liquid |
| Concentration: | 1 ug/uL |
| Recommend dilutions: | The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS, pH 7.4 (0.05% sodium azide). |
| Storage instruction: | This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, store at -20°C or below. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Antigen species / target species: | Human |
| Specificity: | The QD-9 antibody can specifically detect demyelinating lesions in brains with multiple sclerosis, multiple system atrophy (MSA), as well as infarcted brains. The QD-9 antibody is, therefore, a very useful tool for detecting demyelination but not myelin in normal brain. |
| Reactivity: | Human |
| Application image: | ![]() |
| Application image note: | Double staining with MBP monoclonal antibody, clone QD-9 (Cat # MAB8817) and anti-ubiquitin in a multiple system atrophy (MSA) case (moderately affected cerebella medulla). The distribution of Cat # MAB8817 (purple) is different from that of ubiquinated glial cytoplasmic inclusions (GCIs, brown), medulla (case M6). Ubiquinated GCIs and Cat # MAB8817 positive fibers are detected. Note that Cat # MAB8817 does not stain the GCIs. |
| Applications: | IHC,WB-Ti |
| Shipping condition: | Dry Ice |