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| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Mouse |
| Applications | WB,IP |
| Brand: | Abnova |
| Reference: | MAB8228 |
| Product name: | PCSK9 (prodomain) monoclonal antibody, clone KS-2C8 |
| Product description: | Mouse monoclonal antibody raised against full length recombinant PCSK9. |
| Clone: | KS-2C8 |
| Isotype: | IgG1 |
| Gene id: | 255738 |
| Gene name: | PCSK9 |
| Gene alias: | FH3|HCHOLA3|LDLCQ1|NARC-1|NARC1 |
| Gene description: | proprotein convertase subtilisin/kexin type 9 |
| Immunogen: | Recombinant His fusion protein corresponding to full length human PCSK9. |
| Form: | Liquid |
| Recommend dilutions: | Western Blot (0.5-1 ug/mL) Immunoprecipitation (1-2 ug/sample) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In 10 mM phosphate buffer, 150 mM NaCl, pH 7.5 (50% glycerol) |
| Storage instruction: | Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Antigen species / target species: | Human |
| Specificity: | This antibody detects endogenous mature form of PCSK9 prodomain, does not react with pro-form of PCSK9. |
| Reactivity: | Human |
| Application image: | ![]() |
| Application image note: | Western blot analysis of PCSK9 (prodomain) monoclonal antibody, clone KS-2C8 (Cat # MAB8228). Lane 1: purified PCSK9-His Lane 2 : PCSK9-His expressing 293 cell Lane 3 : HepG2 culture supernatant Lane 4 : HepG2 cell Lane 5 : A-431 cell |
| Applications: | WB,IP |
| Shipping condition: | Dry Ice |
| Publications: | Effect of mutations in the PCSK9 gene on the cell surface LDL receptors.Cameron J, Holla OL, Ranheim T, Kulseth MA, Berge KE, Leren TP. Hum Mol Genet. 2006 May 1;15(9):1551-8. Epub 2006 Mar 28. |