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Data sheet of SNCA (nitrated) monoclonal antibody, clone 24.8
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Mouse |
| Applications | IHC-P,WB-Re |
More info about SNCA (nitrated) monoclonal antibody, clone 24.8
| Brand: | Abnova |
| Reference: | MAB7378 |
| Product name: | SNCA (nitrated) monoclonal antibody, clone 24.8 |
| Product description: | Mouse monoclonal antibody raised against nitrated SNCA. |
| Clone: | 24.8 |
| Isotype: | IgG1, kappa |
| Gene id: | 6622 |
| Gene name: | SNCA |
| Gene alias: | MGC110988|NACP|PARK1|PARK4|PD1 |
| Gene description: | synuclein, alpha (non A4 component of amyloid precursor) |
| Immunogen: | Nitrated human SNCA. |
| Form: | Liquid |
| Recommend dilutions: | Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500) Western Blot (1:500-1:1500) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In Tris-glycine, 150 mM NaCl, pH 7.5 (0.05% sodium azide) |
| Storage instruction: | Store at 4°C for short term. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Antigen species / target species: | Human |
| Specificity: | This antibody is useful for Western blot where a band is seen at ~14 KDa. Epitope: 2 nitrated residues Y125, Y133. |
| Reactivity: | Human |
| Application image: |  |
| Application image note: | Western blot of (A) Nitrated SNCA protein and (B) non-nitrated SNCA protein with SNCA (nitrated) monoclonal antibody, clone 24.8 (Cat # MAB7378). |
| Applications: | IHC-P,WB-Re |
| Shipping condition: | Dry Ice |
| Publications: | Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions.Giasson BI, Duda JE, Murray IV, Chen Q, Souza JM, Hurtig HI, Ischiropoulos H, Trojanowski JQ, Lee VM. Science. 2000 Nov 3;290(5493):985-9. |