| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Mouse |
| Applications | WB,ICC,IHC,Flow Cyt |
| Brand: | Abnova |
| Reference: | MAB6450 |
| Product name: | ICAM1 monoclonal antibody, clone 1H4 |
| Product description: | Mouse monoclonal antibody raised against native ICAM1. |
| Clone: | 1H4 |
| Isotype: | IgG2b |
| Gene id: | 3383 |
| Gene name: | ICAM1 |
| Gene alias: | BB2|CD54|P3.58 |
| Gene description: | intercellular adhesion molecule 1 |
| Immunogen: | Raji cells and spleen cells fused with NS1 cells. |
| Form: | Liquid |
| Recommend dilutions: | Flow Cytometry (1 ug/mL) Immunocytochemistry Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) Immunohistochemistry (frozen sections) (5-10 ug/mL) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS, 300 mM NaCl, pH 7.4 |
| Storage instruction: | Store at 4°C. Do not freeze. Aliquot to avoid repeated freezing and thawing. |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Antigen species / target species: | Human |
| Specificity: | This antibody reacts with CD54 (ICAM-1), a 85-110 KDa type I transmembrane glycoprotein (receptor for rhinovirus) expressed on activated endothelial cells, Tlymphocytes, B lymphocytes, monocytes, macrophages, granulocytes and dendritic cells; the expression of CD54 is upregulated by activation. |
| Reactivity: | Human |
| Application image: | ![]() |
| Application image note: | Surface staining of U-937 (human histiocytic lymphoma cell line) with ICAM1 monoclonal antibody, clone 1H4 (PE). Total viable cells were used for analysis. |
| Applications: | WB,ICC,IHC,Flow Cyt |
| Shipping condition: | Blue Ice |
| Publications: | Plasmodium falciparum-infected erythrocytes bind ICAM-1 at a site distinct from LFA-1, Mac-1, and human rhinovirus.Ockenhouse CF, Betageri R, Springer TA, Staunton DE. Cell. 1992 Jan 10;68(1):63-9. |